吡柔比星与羟基喜树碱治疗浅表性膀胱癌术后的短期疗效对比(1)
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【摘要】目的评价经尿道膀胱肿瘤电切术(TURBT)联合羟基喜树碱或吡柔比星膀胱内灌注治疗浅表性膀胱癌的疗效。方法36例浅表性膀胱癌患者行TURBt术，其中22例术后1周开始行吡柔比星膀胱灌注，另外14例行羟基喜树碱膀胱灌注化疗，定期复查B超和膀胱镜，随访3年观察肿瘤的复发率。结果吡柔比星化疗1例失访，其余21例患者术后3年、5年的肿瘤复发率分别为19.05%、28.57%；14例行羟基喜树碱灌注后3年、5年时的肿瘤复发率分别为21.43%、42.85%。结论吡柔比星与羟基喜树碱对浅表性膀胱癌的疗效确切，无明显差异性，均可有效降低膀胱癌的近期复发率。
【关键词】膀胱癌；吡柔比星；羟基喜树碱
Comparison the short-term efficacy of THP and Hydroxycamptothecin on patients with superficial bladder cancer after transurethral resection LI Si-yuan.The People’s Hospital of Huining County,Huining 730700,China
【Abstract】ObjectiveTo evaluate the efficacy of transurethral resection of bladder tumor (TURBT) combined with pirarubicin (THP) or hydroxycamptothecin intravesical administration to prevent recurrence of superficial bladder cancer.Methods36 patients with superficial bladder cancer undergo TURBT, of which 22 cases with THP intravesical administration after 1 week of, another 14 cases with Hydroxycamptothecin chemotherapy ......
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